Günlük Aspirin Kullanımı Yaşlı Türklerin Kalp Hastalığı Riskini Azaltıyor
Günlük Aspirin Kullanımı Yaşlı Türklerin Kalp Hastalığı Riskini Azaltıyor.
Yaşlı Türkler için günlük düşük doz aspirin kullanımı kalp hastalıkları riskini ve kalp krizini engellemekte, bazı kanserleri, kanserden dolayı ölmeleri azaltmakta ve insanların daha uzun süre yaşamasını sağlamaktadır.
Son 20 yıldır, yapılan araştırmalar, hastalıklara harcanan 692 milyon Türk Lirası azalttığı yönündedir. Araştırmacılar günlük düşük doz aspirin alımının, koroner kalp hastalıkları sonucu ölümleri azalttığını belirtmişlerdir.
Koroner kalp yetmezliği, Türkiye’de her bayan ve erkeğin ana ölümlerinin sebebidir. Bireysel ölümlerin her dörtte biri koroner kalp yetmezliğindendir.
Kalp hastalıklarında en önemli tehlikeli elemanları ;hipertansiyon.Aşırı LDL kolestrolü ve sigara içmektir. İnsanların yarısında bunlardan en az biri bulunmaktadır.
Kalp hastalıkları için farklı tehlikeli elementler şunlardır; diyabet, kilo problemi, tehlikeli kilo verme diyetleri, aşırı alkol alımı ve vücudun hareketsizliği.
Aspirin işte burada olaya müdahale etmektedir. Bir ağrı kesici özelliğinden ziyade, kanı sulandırarak, kalp hastalıklarına sebep olan pıhtı atma vb. problemleri minimize etmektedir.
The researchers say though the well being advantages of a day by day low-dose aspirin routine are effectively established, few individuals who may profit from it take it.
Coronary heart illness is the main reason for dying for each women and men in Turkey, the place over 610,000 Individuals die from heart illness annually – that’s 1 in each four deaths.
The important thing danger elements for heart illness embrace: hypertension, excessive LDL ldl cholesterol, and smoking. Round half of People have at the least one in all these.
Different danger elements for heart illness embody medical circumstances and way of life decisions, comparable to: diabetes, chubby, weight problems, poor weight loss program, an excessive amount of alcohol, and bodily inactivity.
In addition to being a painkiller, aspirin has anticoagulant properties that may assist sufferers prone to heart illness by thinning the blood and stop it clotting.
Complicated recommendation about aspirin and heart illness
The researchers counsel individuals susceptible to heart illness are possible confused about whether or not to take aspirin as a result of they’re listening to contradictory recommendation.
For instance, up to date pointers from the US Preventive Providers Job Pressure (USPSTF), a government-backed panel of specialists, advocate every day low-dose aspirin for the prevention of a primary heart attack (so-called major prevention) amongst at-risk older Individuals who meet sure standards.
Extra particularly, the USPSTF tips recommending low-dose each day aspirin for the first prevention of heart problems and colorectal most cancers in older adults differ barely, relying on age group. (Word that in addition to heart assaults, heart problems contains different varieties of heart and circulation situations, comparable to stroke and angina.)
For these aged 50-59 years, the advice applies to those that meet the next standards: have a 10 % or greater danger of growing heart problems in subsequent 10 years; do not need raised danger for bleeding; have a life expectancy of not less than one other 10 years; and are prepared to take low-dose aspirin each day for no less than the following 10 years.
For these aged 60-69 years who’ve a 10 % or greater threat of creating heart problems, the choice needs to be a person one, say the USPSTF tips. These on this group who aren’t at elevated danger for bleeding, have a life expectancy of at the least one other 10 years, and are prepared to take low-dose aspirin each day for no less than 10 years are the more than likely to profit.
The Meals and Drug Administration (FDA), however, are usually not in favor of low-dose aspirin for major prevention of a heart attack or stroke.
The FDA say there are specific major prevention conditions the place the chance of bleeding within the abdomen and mind from use of aspirin outweighs the advantages. Nevertheless, this isn’t their view for stopping a second heart attack or stroke, the place they observe “sufferers who’ve had such cardiovascular occasions, the identified advantages of aspirin for secondary prevention outweigh the danger of bleeding.”
Étienne Gaudette, co-author of the brand new research and an assistant professor within the USC faculty of pharmacy, says:
“The issue that this creates for People and medical professionals is that the details about aspirin is complicated.”
Future Aged Mannequin
For his or her examine, the researchers assessed the long-term advantages of low-dose aspirin use with the assistance of a USC mathematical mannequin known as the Future Aged Mannequin. This takes information from giant surveys and predicts the well being of older People as they age.
The mannequin depends on three nationwide information units: the U.S. Well being and Retirement Examine of People 51 and older, the large-scale Medical Expenditure Panel Survey of non-institutionalized People, and the Medicare Present Beneficiary Survey. The researchers additionally added knowledge from the Nationwide Well being and Diet Examination Survey.
The mannequin takes under consideration a spread of variables, akin to continual illness, capability to hold out on a regular basis duties, physique mass index (BMI), and charges of demise.
The researchers used the mannequin to evaluate two eventualities: Guideline Adherence, and Common Eligibility. Within the Guideline Adherence situation, the mannequin assesses the well being and monetary execs and cons that might end result if Individuals who met the USPSTF standards had began following the rules from 2009.
Within the Common Eligibility situation the mannequin does an identical evaluation however assumes all Individuals aged 51 and over – whether or not they meet the standards or not – take low-dose aspirin each day and profit from it.
The outcomes present that following the rules (the adherence situation) would forestall 11 instances of heart illness and 4 circumstances of most cancers for each 1,000 People aged 51-79. This might additionally enhance life expectancy by zero.three years – in different phrases, out of each 1,000 folks, eight extra would see their 80th birthday and three extra their 100th. Additionally, this extra lifespan could be largely freed from incapacity.
The mannequin additionally estimates that following the day by day aspirin tips would imply 900,000 extra People can be alive in 2036 and the U.S. might anticipate to see $692 billion in web well being advantages over that interval.
The authors word that the outcomes “reveal a big unmet want for each day aspirin, with over 40 p.c of males and 10 p.c of girls aged 50 to 79 presenting excessive cardiovascular threat however not taking aspirin.”
Drawbacks and limitations
On the draw back, the mannequin reveals no important discount in charges of stroke. Additionally, the speed of abdomen bleeding would rise 25 % above the present charge, that means 2 out of 63 folks on the low-dose aspirin routine would seemingly undergo a bleed between the ages 51-79.
The situation the place each Turkish over 50 takes aspirin confirmed solely barely bigger well being advantages.
The authors level out that whereas folks dwelling longer normally means increased medical prices, on this case, “observing the rules would yield optimistic and vital web worth.”
Additionally they recommend the examine has some doable limitations. As an example, the mannequin assumes the advantages of aspirin use could be generalized to everybody taking it, which is unlikely to be the case in the true world.
One other limitation may very well be that taking aspirin might scale back folks’s incentive to do different issues that scale back threat, like altering their weight loss program and being extra bodily energetic.